Perkinsus infection is associated with alterations in the level of global DNA methylation of gills and gastrointestinal tract of the oyster Crassostrea gasar

Bivalves are filter feeders that obtain food from seawater that may contain infectious agents, such as the protozoan parasites Perkinsus marinus and P. olseni that are associated with massive mortalities responsible for losses in the aquaculture industry. Despite all physical and chemical barriers, microorganisms cross epithelia and infect host tissues to cause pathologies. Epigenetics mechanisms … Continue reading Perkinsus infection is associated with alterations in the level of global DNA methylation of gills and gastrointestinal tract of the oyster Crassostrea gasar

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Morphological and functional characterization of the hemocytes from the pearl oyster Pteria hirundo and their immune responses against Vibrio infections

Hemocyte populations of the pearl oyster Pteria hirundo were characterized at morphological, ultrastructural and functional levels. Three main hemocyte populations were identified: hyalinocytes, granulocytes and blast-like cells. Hyalinocytes were the most abundant population (88.2%) characterized by the presence of few or no granules in the cytoplasm and composed by two subpopulations, large and small hyalinocytes. … Continue reading Morphological and functional characterization of the hemocytes from the pearl oyster Pteria hirundo and their immune responses against Vibrio infections

Oysters under threat from deadly herpes virus that is spreading around the world

THE world could soon be facing an oyster shortage as a deadly herpes virus is threatening to devastate oyster populations. The virus known as Ostreid herpesvirus 1 (OsHV-1), is impacting Pacific oysters, which is the most popular species to eat due to their large size and experts are worried it could continue to spread around … Continue reading Oysters under threat from deadly herpes virus that is spreading around the world

Metabolomic applications in marine mollusc development and aquaculture

Metabolomics is a rapidly emerging discipline within functional genomics to better understand biochemical phenotypes across a range of biological systems. The approach has many demonstrated applications in aquatic biology, but has not yet been applied to study early lifestages of marine molluscs. This Thesis evaluates metabolomics as an approach to characterise early lifestage phenotypes of … Continue reading Metabolomic applications in marine mollusc development and aquaculture

The RNA-seq analysis suggests a potential multi-component complement system in oyster Crassostrea gigas

The complement system is one of the major effector mechanisms of immune system, playing essential roles in both the innate and adaptive immune responses. In the present study, the counterparts of vertebrate complement components were identified by screening the sequenced genome of Crassostrea gigas, resulting in the identification of 792 gene models containing complement-related domains. … Continue reading The RNA-seq analysis suggests a potential multi-component complement system in oyster Crassostrea gigas

The first invertebrate NFIL3 transcription factor with role in immune defense identified from the Hong Kong oyster, Crassostrea hongkongensis

NFIL3 (nuclear factor interleukin 3-regulated) is a basic leucine zipper type transcription factor that mediates a variety of immune responses in vertebrates. However, the sequence information and function of NFIL3 homologs in invertebrates, especially mollusks, remains unknown. In the present study, the first NFIL3 homolog was identified in a marine mollusk, Crassostrea hongkongensis (designated as … Continue reading The first invertebrate NFIL3 transcription factor with role in immune defense identified from the Hong Kong oyster, Crassostrea hongkongensis

Mortality in Crassostrea gigas oysters in Ireland during 2012

OsHV-1 mu Var-related mortality is well described in several countries, including France. In Ireland, however, clear patterns in relation to the incidence and impact of this virus have been difficult to identify, at least in part because seawater temperatures rarely exceed 16 degrees C, a recognised threshold for OsHV-1 mu Var-related mortality, for prolonged periods. … Continue reading Mortality in Crassostrea gigas oysters in Ireland during 2012