Specific pathogen recognition by multiple innate immune sensors in an invertebrate

Detection of pathogens by all living organisms is the primary step needed to implement a coherent and efficient immune response. This implies a mediation by different soluble and/or membrane-anchored proteins related to innate immune receptors called PRRs (pattern-recognition receptors) to trigger immune signaling pathways. In most invertebrates, their roles have been inferred by analogy to … Continue reading Specific pathogen recognition by multiple innate immune sensors in an invertebrate

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OsHV-1 and notifiable protozoa in healthy Crassostrea corteziensis cultured in two distant areas of the Gulf of California

Infectious diseases have been a major limiting factor for large scale production of oyster farming. Several factors have contributed to the emergence and spread of infectious diseases in all cultivation sites around the world. Therefore, the prevention and control of diseases has become a priority for the sustainability of global aquaculture. Crassostrea corteziensis is a … Continue reading OsHV-1 and notifiable protozoa in healthy Crassostrea corteziensis cultured in two distant areas of the Gulf of California

Morphological and functional characterization of the hemocytes from the pearl oyster Pteria hirundo and their immune responses against Vibrio infections

Hemocyte populations of the pearl oyster Pteria hirundo were characterized at morphological, ultrastructural and functional levels. Three main hemocyte populations were identified: hyalinocytes, granulocytes and blast-like cells. Hyalinocytes were the most abundant population (88.2%) characterized by the presence of few or no granules in the cytoplasm and composed by two subpopulations, large and small hyalinocytes. … Continue reading Morphological and functional characterization of the hemocytes from the pearl oyster Pteria hirundo and their immune responses against Vibrio infections

Metabolomic applications in marine mollusc development and aquaculture

Metabolomics is a rapidly emerging discipline within functional genomics to better understand biochemical phenotypes across a range of biological systems. The approach has many demonstrated applications in aquatic biology, but has not yet been applied to study early lifestages of marine molluscs. This Thesis evaluates metabolomics as an approach to characterise early lifestage phenotypes of … Continue reading Metabolomic applications in marine mollusc development and aquaculture

Comparative and evolutionary analysis of an adapter molecule MyD88 in invertebrate metazoans

The myeloid differentiation factor 88 (MyD88) is an essential adapter in Toll-like receptor (TLR) signalling pathways, with TLR the first pattern-recognition receptor (PRR) that was discovered in Drosophila. In the present study, a MyD88 gene was identified and characterized from a commercially important shellfish, Scapharca subcrenata, including a DEATH domain and TIR domain conserved within … Continue reading Comparative and evolutionary analysis of an adapter molecule MyD88 in invertebrate metazoans

The first invertebrate NFIL3 transcription factor with role in immune defense identified from the Hong Kong oyster, Crassostrea hongkongensis

NFIL3 (nuclear factor interleukin 3-regulated) is a basic leucine zipper type transcription factor that mediates a variety of immune responses in vertebrates. However, the sequence information and function of NFIL3 homologs in invertebrates, especially mollusks, remains unknown. In the present study, the first NFIL3 homolog was identified in a marine mollusk, Crassostrea hongkongensis (designated as … Continue reading The first invertebrate NFIL3 transcription factor with role in immune defense identified from the Hong Kong oyster, Crassostrea hongkongensis

Manual of diagnostic tests for aquatic animals

Valid laboratory results are essential for Aquatic Animal Health Services to implement a range of programmes for diagnosis, surveillance and trade. This Manual of Diagnostic Tests for Aquatic Animals (Aquatic Manual) supports Aquatic Animal Health Services to provide effective laboratory testing for pathogenic agents that may adversely affect aquatic animals. (...) The World Organisation for Animal Health … Continue reading Manual of diagnostic tests for aquatic animals