LRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) recognizes bacteria and promotes hemocytic phagocytosis in the Pacific oyster Crassostrea gigas

In bivalve mollusks, circulating hemocyte mediated phagocytosis is one of the primary ways to eliminate invading microbes. Here, we have identified one CgLRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) in the Crassostrea gigas as a novel transmembrane LRR (Leucine-rich repeat) domain containing protein in C. gigas, homologous to the jawless fish VLR protein, that … Continue reading LRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) recognizes bacteria and promotes hemocytic phagocytosis in the Pacific oyster Crassostrea gigas

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Development of a duplex Taqman real-time PCR assay for rapid identification of Vibrio splendidus-related and V. aestuarianus strains from bacterial cultures

To enable the rapid and accurate identification of Vibrio splendidus-related and V. aestuarianus strains associated with Pacific cupped oyster Crassostrea gigas mortality, we developed a duplex Taqman real-time PCR assay and evaluated its efficacy. This technique proved to be rapid, sensitive, and specific and will be particularly valuable for epidemiologic studies. Denis Saulnier, Sophie De … Continue reading Development of a duplex Taqman real-time PCR assay for rapid identification of Vibrio splendidus-related and V. aestuarianus strains from bacterial cultures

Double résistance aux infections dues aux organismes pathogènes Vibrio aestuarianus et OsHV-1 chez l’huître creuse Crassostrea gigas – DORE. Rapport scientifique final de l’étude DORE, convention DPMA-Ifremer 2016

Depuis 2012, le nombre de cas de mortalités d’huîtres creuses adultes (Crassostrea gigas) rapportés dans le cadre des réseaux de surveillance de l’Ifremer, et dans lesquels la bactérie Vibrio aestuarianus a été isolée, a fortement augmenté. Les objectifs de cette étude étaient (1) d’étudier la sensibilité des huîtres C. gigas à une infection à V. … Continue reading Double résistance aux infections dues aux organismes pathogènes Vibrio aestuarianus et OsHV-1 chez l’huître creuse Crassostrea gigas – DORE. Rapport scientifique final de l’étude DORE, convention DPMA-Ifremer 2016

Population-specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae

The consequences of emerging marine diseases on the evolutionary trajectories of affected host populations in the marine realm are largely unexplored. Evolution in response to natural selection depends on the genetic variation of the traits under selection and the interaction of these traits with the environment (GxE). However, in the case of diseases, pathogen genotypes … Continue reading Population-specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae

Comparative study of three C1q domain containing proteins from pacific oyster Crassostrea gigas

C1q domain containing proteins (C1qDCs) are a family of proteins containing a globular head C1q domain (ghC1q) in C-terminus, which serve as pattern recognition receptors (PRRs) and mediate a series of immune responses. In the present study, three C1qDC proteins from pacific oyster Crassostrea gigas (CgC1qDC-2, CgC1qDC-3, CgC1qDC-4) were characterized and comparatively investigated to understand … Continue reading Comparative study of three C1q domain containing proteins from pacific oyster Crassostrea gigas

The RNA-seq analysis suggests a potential multi-component complement system in oyster Crassostrea gigas

The complement system is one of the major effector mechanisms of immune system, playing essential roles in both the innate and adaptive immune responses. In the present study, the counterparts of vertebrate complement components were identified by screening the sequenced genome of Crassostrea gigas, resulting in the identification of 792 gene models containing complement-related domains. … Continue reading The RNA-seq analysis suggests a potential multi-component complement system in oyster Crassostrea gigas

Mortality in Crassostrea gigas oysters in Ireland during 2012

OsHV-1 mu Var-related mortality is well described in several countries, including France. In Ireland, however, clear patterns in relation to the incidence and impact of this virus have been difficult to identify, at least in part because seawater temperatures rarely exceed 16 degrees C, a recognised threshold for OsHV-1 mu Var-related mortality, for prolonged periods. … Continue reading Mortality in Crassostrea gigas oysters in Ireland during 2012