LRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) recognizes bacteria and promotes hemocytic phagocytosis in the Pacific oyster Crassostrea gigas

In bivalve mollusks, circulating hemocyte mediated phagocytosis is one of the primary ways to eliminate invading microbes. Here, we have identified one CgLRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) in the Crassostrea gigas as a novel transmembrane LRR (Leucine-rich repeat) domain containing protein in C. gigas, homologous to the jawless fish VLR protein, that … Continue reading LRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) recognizes bacteria and promotes hemocytic phagocytosis in the Pacific oyster Crassostrea gigas

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Population-specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae

The consequences of emerging marine diseases on the evolutionary trajectories of affected host populations in the marine realm are largely unexplored. Evolution in response to natural selection depends on the genetic variation of the traits under selection and the interaction of these traits with the environment (GxE). However, in the case of diseases, pathogen genotypes … Continue reading Population-specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae

Comparative study of three C1q domain containing proteins from pacific oyster Crassostrea gigas

C1q domain containing proteins (C1qDCs) are a family of proteins containing a globular head C1q domain (ghC1q) in C-terminus, which serve as pattern recognition receptors (PRRs) and mediate a series of immune responses. In the present study, three C1qDC proteins from pacific oyster Crassostrea gigas (CgC1qDC-2, CgC1qDC-3, CgC1qDC-4) were characterized and comparatively investigated to understand … Continue reading Comparative study of three C1q domain containing proteins from pacific oyster Crassostrea gigas

Infection dynamics of a V. splendidus strain pathogenic to Mytilus edulis: In vivo and in vitro interactions with hemocytes

The pathogenic strain V. splendidus 10/068 1T1 has previously been reported for its virulence to the blue mussel and for its capacity to alter immune responses. In this study, we expanded the knowledge on hemocyte-pathogen interactions by using in vitro and in vivo assays. V. splendidus 10/068 1T1 severely inhibited cell adhesion and acidic vacuole formation unlike the innocuous … Continue reading Infection dynamics of a V. splendidus strain pathogenic to Mytilus edulis: In vivo and in vitro interactions with hemocytes

Ocean acidification and pathogen exposure modulate the immune response of the edible mussel Mytilus chilensis

Ocean acidification (OA) is one of the main consequences of increasing atmospheric carbon dioxide (CO2), impacting key biological processes of marine organisms such as development, growth and immune response. However, there are scarce studies on the influence of OA on marine invertebrates' ability to cope with pathogens. This study evaluated the single and combined effects … Continue reading Ocean acidification and pathogen exposure modulate the immune response of the edible mussel Mytilus chilensis

Disease and mortality among Yesso scallops Patinopecten yessoensis putatively caused by infection with Francisella halioticida

During the fall of 2015, up to 40% mortality occurred in juvenile Yesso scallops Patinopecten yessoensis at an aquaculture site in Baynes Sound, British Columbia, Canada. Macroscopic lesions were present in 11% of the scallops, and histopathology consisting of multifocal and diffuse haemocyte infiltration was observed in 44% of the specimens examined. Histologically, small Gram-negative … Continue reading Disease and mortality among Yesso scallops Patinopecten yessoensis putatively caused by infection with Francisella halioticida

Necrotic disease in bivalve larval cultures

The health of marine bivalve larvae is greatly affected by bacteria in the environment particularly when reared in marine hatcheries. This is generally because high stocking densities resulting in high organic loads of both food and faeces, can support increased bacterial growth and biomass levels. Increased bacterial load can lead to larval disease referred to … Continue reading Necrotic disease in bivalve larval cultures