The roles of galectins in parasitic infections

Galectins is a family of multifunctional lectins. Fifteen galectins have been identified from a variety of cells and tissues of vertebrates and invertebrates. Galectins have been shown to play pivotal roles in host–pathogen interaction such as adhesion of pathogens to host cells and activation of host innate and adaptive immunity. In recent years, the roles … Continue reading The roles of galectins in parasitic infections

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Comparative population genetic study of an important marine parasite from New Zealand flat oysters

The comparative genetic structure of hosts and parasites can reveal constraints acting on parasite dispersal among host populations and the evolution of local adaptation. We sampled New Zealand flat oysters Ostrea chilensis from 12 sites throughout New Zealand to (1) determine the distribution and prevalence of the haplosporidian parasites Bonamia exitiosa and B. ostreae, and … Continue reading Comparative population genetic study of an important marine parasite from New Zealand flat oysters

A potential microRNA regulation of immune-related genes in invertebrate haemocytes

Bivalve mollusks have been employed as sentinel organisms in environmental health programs due to their sedentary lifestyle, filter-feeding behavior and their ability to accumulate pathogens or toxin molecules inside tissues. Endocrine disrupting chemicals (EDCs) can be up taken and bioaccumulated, and due to sensibility of mollusks to these EDCs, being able to cause immune alterations. … Continue reading A potential microRNA regulation of immune-related genes in invertebrate haemocytes

LRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) recognizes bacteria and promotes hemocytic phagocytosis in the Pacific oyster Crassostrea gigas

In bivalve mollusks, circulating hemocyte mediated phagocytosis is one of the primary ways to eliminate invading microbes. Here, we have identified one CgLRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) in the Crassostrea gigas as a novel transmembrane LRR (Leucine-rich repeat) domain containing protein in C. gigas, homologous to the jawless fish VLR protein, that … Continue reading LRFN (leucine-rich repeat and fibronectin type-III domain-containing protein) recognizes bacteria and promotes hemocytic phagocytosis in the Pacific oyster Crassostrea gigas

Oyster virus may cause devastating results for Tasmania

Oyster supplies in Tasmania are being threatened by a viral disease, which is concerning to producers ahead of the Christmas period. The concern in the sector stems from the fact that the virus causing Pacific Oyster Mortality Syndrome (POMS), which is harmless to humans, weakens oysters and makes them lose their ability to close their … Continue reading Oyster virus may cause devastating results for Tasmania

Molecular characterization and protein localization of the antimicrobial peptide big defensin from the scallop Argopecten purpuratus after Vibrio splendidus challenge

Big defensins are antimicrobial peptides (AMPs) that are proposed as important effectors of the immune response in mollusks, chelicerates and chordates. At present, only two members of the big defensin family have been identified in scallop. In the present work, a cDNA sequence encoding a new big defensin homologue was characterized from the scallop Argopecten … Continue reading Molecular characterization and protein localization of the antimicrobial peptide big defensin from the scallop Argopecten purpuratus after Vibrio splendidus challenge

Phylogeography and connectivity of molluscan parasites: Perkinsus spp. in Panama and beyond

Panama is a major hub for commercial shipping between two oceans, making it an ideal location to examine parasite biogeography, potential invasions, and the spread of infectious agents. Our goals were to (i) characterise the diversity and genetic connectivity of Perkinsus spp. haplotypes across the Panamanian Isthmus and (ii) combine these data with sequences from … Continue reading Phylogeography and connectivity of molluscan parasites: Perkinsus spp. in Panama and beyond